node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACVR2B | GDF11 | ENSNLEP00000006554 | ENSNLEP00000021360 | Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. | TGF_BETA_2 domain-containing protein. | 0.998 |
ACVR2B | SMAD2 | ENSNLEP00000006554 | ENSNLEP00000023604 | Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. | Mothers against decapentaplegic homolog. | 0.973 |
ACVR2B | SMAD7 | ENSNLEP00000006554 | ENSNLEP00000048725 | Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. | Mothers against decapentaplegic homolog. | 0.660 |
ACVR2B | SMURF2 | ENSNLEP00000006554 | ENSNLEP00000018129 | Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. | E3 ubiquitin-protein ligase. | 0.508 |
ACVR2B | TGFB1 | ENSNLEP00000006554 | ENSNLEP00000016659 | Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. | Transforming growth factor beta; Belongs to the TGF-beta family. | 0.646 |
ACVR2B | TGFB3 | ENSNLEP00000006554 | ENSNLEP00000020116 | Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. | Transforming growth factor beta; Belongs to the TGF-beta family. | 0.451 |
ACVR2B | TGFBR1 | ENSNLEP00000006554 | ENSNLEP00000041209 | Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. | 0.996 |
ACVR2B | TGFBR2 | ENSNLEP00000006554 | ENSNLEP00000005036 | Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. | TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] | 0.645 |
ENSNLEP00000036875 | TGFB1 | ENSNLEP00000036875 | ENSNLEP00000016659 | Peptidylprolyl isomerase. | Transforming growth factor beta; Belongs to the TGF-beta family. | 0.611 |
ENSNLEP00000036875 | TGFBR1 | ENSNLEP00000036875 | ENSNLEP00000041209 | Peptidylprolyl isomerase. | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. | 0.993 |
ENSNLEP00000036875 | TGFBR2 | ENSNLEP00000036875 | ENSNLEP00000005036 | Peptidylprolyl isomerase. | TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] | 0.479 |
FKBP1A | TGFB1 | ENSNLEP00000027944 | ENSNLEP00000016659 | Peptidylprolyl isomerase. | Transforming growth factor beta; Belongs to the TGF-beta family. | 0.611 |
FKBP1A | TGFBR1 | ENSNLEP00000027944 | ENSNLEP00000041209 | Peptidylprolyl isomerase. | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. | 0.993 |
FKBP1A | TGFBR2 | ENSNLEP00000027944 | ENSNLEP00000005036 | Peptidylprolyl isomerase. | TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] | 0.479 |
GDF11 | ACVR2B | ENSNLEP00000021360 | ENSNLEP00000006554 | TGF_BETA_2 domain-containing protein. | Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. | 0.998 |
GDF11 | SMAD2 | ENSNLEP00000021360 | ENSNLEP00000023604 | TGF_BETA_2 domain-containing protein. | Mothers against decapentaplegic homolog. | 0.545 |
GDF11 | TGFBR1 | ENSNLEP00000021360 | ENSNLEP00000041209 | TGF_BETA_2 domain-containing protein. | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. | 0.997 |
GDF11 | TGFBR2 | ENSNLEP00000021360 | ENSNLEP00000005036 | TGF_BETA_2 domain-containing protein. | TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] | 0.434 |
SMAD2 | ACVR2B | ENSNLEP00000023604 | ENSNLEP00000006554 | Mothers against decapentaplegic homolog. | Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. | 0.973 |
SMAD2 | GDF11 | ENSNLEP00000023604 | ENSNLEP00000021360 | Mothers against decapentaplegic homolog. | TGF_BETA_2 domain-containing protein. | 0.545 |