Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ROCK1Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1359 aa)    
Predicted Functional Partners:
ROCK2
Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity.
  
0.999
RHOA
Ras homolog family member A.
   
 0.998
PPP1R12A
Protein phosphatase 1 regulatory subunit.
   
 0.992
LOC100592546
ANK_REP_REGION domain-containing protein.
   
 0.977
LIMK2
LIM domain kinase 2.
    
0.968
GAB1
GRB2 associated binding protein 1.
   
  0.956
CTNNB1
Catenin beta 1.
    
 0.955
MYL12B
Myosin light chain 12B.
    
 0.954
MYL9
Myosin light chain 9.
    
 0.953
ENSNLEP00000036737
Uncharacterized protein.
   
 0.953
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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