| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| FZD6 | LGR4 | ENSNLEP00000004540 | ENSNLEP00000021686 | Frizzled class receptor 6; Belongs to the G-protein coupled receptor Fz/Smo family. | Leucine rich repeat containing G protein-coupled receptor 4. | 0.716 |
| FZD6 | LGR5 | ENSNLEP00000004540 | ENSNLEP00000045778 | Frizzled class receptor 6; Belongs to the G-protein coupled receptor Fz/Smo family. | Leucine rich repeat containing G protein-coupled receptor 5. | 0.930 |
| FZD6 | LRP5 | ENSNLEP00000004540 | ENSNLEP00000007969 | Frizzled class receptor 6; Belongs to the G-protein coupled receptor Fz/Smo family. | LDL receptor related protein 5. | 0.599 |
| FZD6 | LRP6 | ENSNLEP00000004540 | ENSNLEP00000004278 | Frizzled class receptor 6; Belongs to the G-protein coupled receptor Fz/Smo family. | Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. | 0.971 |
| FZD6 | RNF43 | ENSNLEP00000004540 | ENSNLEP00000034142 | Frizzled class receptor 6; Belongs to the G-protein coupled receptor Fz/Smo family. | RING-type domain-containing protein. | 0.958 |
| LGR4 | FZD6 | ENSNLEP00000021686 | ENSNLEP00000004540 | Leucine rich repeat containing G protein-coupled receptor 4. | Frizzled class receptor 6; Belongs to the G-protein coupled receptor Fz/Smo family. | 0.716 |
| LGR4 | LGR5 | ENSNLEP00000021686 | ENSNLEP00000045778 | Leucine rich repeat containing G protein-coupled receptor 4. | Leucine rich repeat containing G protein-coupled receptor 5. | 0.996 |
| LGR4 | LGR6 | ENSNLEP00000021686 | ENSNLEP00000021981 | Leucine rich repeat containing G protein-coupled receptor 4. | Leucine rich repeat containing G protein-coupled receptor 6. | 0.924 |
| LGR4 | LRP5 | ENSNLEP00000021686 | ENSNLEP00000007969 | Leucine rich repeat containing G protein-coupled receptor 4. | LDL receptor related protein 5. | 0.527 |
| LGR4 | LRP6 | ENSNLEP00000021686 | ENSNLEP00000004278 | Leucine rich repeat containing G protein-coupled receptor 4. | Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. | 0.949 |
| LGR4 | RNF43 | ENSNLEP00000021686 | ENSNLEP00000034142 | Leucine rich repeat containing G protein-coupled receptor 4. | RING-type domain-containing protein. | 0.905 |
| LGR4 | RSPO1 | ENSNLEP00000021686 | ENSNLEP00000014132 | Leucine rich repeat containing G protein-coupled receptor 4. | R-spondin 1. | 0.985 |
| LGR4 | RSPO2 | ENSNLEP00000021686 | ENSNLEP00000049090 | Leucine rich repeat containing G protein-coupled receptor 4. | R-spondin 2. | 0.998 |
| LGR4 | RSPO3 | ENSNLEP00000021686 | ENSNLEP00000017155 | Leucine rich repeat containing G protein-coupled receptor 4. | R-spondin 3. | 0.994 |
| LGR4 | RSPO4 | ENSNLEP00000021686 | ENSNLEP00000011444 | Leucine rich repeat containing G protein-coupled receptor 4. | R-spondin 4. | 0.993 |
| LGR5 | FZD6 | ENSNLEP00000045778 | ENSNLEP00000004540 | Leucine rich repeat containing G protein-coupled receptor 5. | Frizzled class receptor 6; Belongs to the G-protein coupled receptor Fz/Smo family. | 0.930 |
| LGR5 | LGR4 | ENSNLEP00000045778 | ENSNLEP00000021686 | Leucine rich repeat containing G protein-coupled receptor 5. | Leucine rich repeat containing G protein-coupled receptor 4. | 0.996 |
| LGR5 | LGR6 | ENSNLEP00000045778 | ENSNLEP00000021981 | Leucine rich repeat containing G protein-coupled receptor 5. | Leucine rich repeat containing G protein-coupled receptor 6. | 0.925 |
| LGR5 | LRP5 | ENSNLEP00000045778 | ENSNLEP00000007969 | Leucine rich repeat containing G protein-coupled receptor 5. | LDL receptor related protein 5. | 0.873 |
| LGR5 | LRP6 | ENSNLEP00000045778 | ENSNLEP00000004278 | Leucine rich repeat containing G protein-coupled receptor 5. | Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. | 0.949 |
