node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
GIN1 | PGBD5 | ENSNLEP00000013477 | ENSNLEP00000017369 | Gypsy retrotransposon integrase 1. | Uncharacterized protein. | 0.579 |
GIN1 | PTGR2 | ENSNLEP00000013477 | ENSNLEP00000019499 | Gypsy retrotransposon integrase 1. | Uncharacterized protein. | 0.721 |
GIN1 | RAG1 | ENSNLEP00000013477 | ENSNLEP00000021806 | Gypsy retrotransposon integrase 1. | V(D)J recombination-activating protein 1; Catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T- lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break [...] | 0.685 |
GIN1 | RAG2 | ENSNLEP00000013477 | ENSNLEP00000021807 | Gypsy retrotransposon integrase 1. | Recombination activating 2. | 0.658 |
GIN1 | ZMYM2 | ENSNLEP00000013477 | ENSNLEP00000048281 | Gypsy retrotransposon integrase 1. | Zinc finger MYM-type containing 2. | 0.672 |
GIN1 | ZMYM3 | ENSNLEP00000013477 | ENSNLEP00000046604 | Gypsy retrotransposon integrase 1. | Zinc finger MYM-type containing 3. | 0.730 |
GIN1 | ZNF451 | ENSNLEP00000013477 | ENSNLEP00000003506 | Gypsy retrotransposon integrase 1. | Zinc finger protein 451. | 0.654 |
GTF2I | HDAC2 | ENSNLEP00000010670 | ENSNLEP00000038371 | General transcription factor IIi. | Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. | 0.669 |
GTF2I | KDM1A | ENSNLEP00000010670 | ENSNLEP00000031853 | General transcription factor IIi. | Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. | 0.639 |
GTF2I | ZMYM2 | ENSNLEP00000010670 | ENSNLEP00000048281 | General transcription factor IIi. | Zinc finger MYM-type containing 2. | 0.647 |
GTF2I | ZMYM3 | ENSNLEP00000010670 | ENSNLEP00000046604 | General transcription factor IIi. | Zinc finger MYM-type containing 3. | 0.710 |
HDAC2 | GTF2I | ENSNLEP00000038371 | ENSNLEP00000010670 | Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. | General transcription factor IIi. | 0.669 |
HDAC2 | KDM1A | ENSNLEP00000038371 | ENSNLEP00000031853 | Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. | Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. | 0.993 |
HDAC2 | ZMYM2 | ENSNLEP00000038371 | ENSNLEP00000048281 | Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. | Zinc finger MYM-type containing 2. | 0.866 |
HDAC2 | ZMYM3 | ENSNLEP00000038371 | ENSNLEP00000046604 | Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. | Zinc finger MYM-type containing 3. | 0.790 |
KDM1A | GTF2I | ENSNLEP00000031853 | ENSNLEP00000010670 | Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. | General transcription factor IIi. | 0.639 |
KDM1A | HDAC2 | ENSNLEP00000031853 | ENSNLEP00000038371 | Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. | Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. | 0.993 |
KDM1A | ZMYM2 | ENSNLEP00000031853 | ENSNLEP00000048281 | Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. | Zinc finger MYM-type containing 2. | 0.940 |
KDM1A | ZMYM3 | ENSNLEP00000031853 | ENSNLEP00000046604 | Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. | Zinc finger MYM-type containing 3. | 0.780 |
PGBD5 | GIN1 | ENSNLEP00000017369 | ENSNLEP00000013477 | Uncharacterized protein. | Gypsy retrotransposon integrase 1. | 0.579 |