Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ACTN1Actinin alpha 1. (921 aa)    
Predicted Functional Partners:
VCL
Vinculin.
   
 0.997
ACTN4
Actinin alpha 4.
  
0.996
ACTN2
Actinin alpha 2.
   
 0.989
CTNNA1
Catenin alpha 1.
   
 0.971
CTNNA2
Catenin alpha 2.
   
 0.970
ENSNLEP00000026167
EF-hand domain-containing protein.
   
 0.969
ACTN3
Actinin alpha 3 (gene/pseudogene).
   
 0.967
ACTG1
Actin gamma 1.
   
 0.945
CTNNA3
Catenin alpha 3.
   
 0.932
MAGI1
Membrane associated guanylate kinase, WW and PDZ domain containing 1.
    
 0.927
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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