STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SCUD_LOCUS2950Histone H2A; Belongs to the histone H2A family. (76 aa)    
Predicted Functional Partners:
SCUD_LOCUS9935
Histone H2B; Belongs to the histone H2B family.
  
 0.967
SCUD_LOCUS2411
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
   
 0.944
SCUD_LOCUS9074
Histone H2A; Belongs to the histone H2A family.
   
 0.913
A0A183L6D7
ARID domain-containing protein.
   
 0.834
SCUD_LOCUS1529
Ubiquitin-like domain-containing protein.
   
 0.818
SCUD_LOCUS5774
Histone H3; Belongs to the histone H3 family.
   
 0.808
A0A183K9V4
Histone domain-containing protein.
   
 0.808
A0A183KDH3
Histone H3; Belongs to the histone H3 family.
   
 0.808
A0A183KLT3
Uncharacterized protein.
   
 0.766
SCUD_LOCUS9194
RAWUL domain-containing protein.
    
 0.750
Your Current Organism:
Schistosoma curassoni
NCBI taxonomy Id: 6186
Other names: S. curassoni
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.