| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| A0A183K9T6 | A0A183KIH2 | A0A183K9T6 | A0A183KIH2 | GMPS ATP-PPase domain-containing protein. | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.964 |
| A0A183K9T6 | A0A183KKN6 | A0A183K9T6 | A0A183KKN6 | GMPS ATP-PPase domain-containing protein. | IMPDH domain-containing protein. | 0.994 |
| A0A183K9T6 | A0A183KKQ3 | A0A183K9T6 | A0A183KKQ3 | GMPS ATP-PPase domain-containing protein. | Uncharacterized protein. | 0.991 |
| A0A183K9T6 | A0A183KNM0 | A0A183K9T6 | A0A183KNM0 | GMPS ATP-PPase domain-containing protein. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | 0.544 |
| A0A183K9T6 | A0A183KPI2 | A0A183K9T6 | A0A183KPI2 | GMPS ATP-PPase domain-containing protein. | Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | 0.562 |
| A0A183K9T6 | A0A183KR98 | A0A183K9T6 | A0A183KR98 | GMPS ATP-PPase domain-containing protein. | Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | 0.562 |
| A0A183K9T6 | A0A183KTR4 | A0A183K9T6 | A0A183KTR4 | GMPS ATP-PPase domain-containing protein. | Pribosyltran domain-containing protein. | 0.991 |
| A0A183K9T6 | A0A183KZG5 | A0A183K9T6 | A0A183KZG5 | GMPS ATP-PPase domain-containing protein. | Uncharacterized protein. | 0.946 |
| A0A183K9T6 | SCUD_LOCUS3004 | A0A183K9T6 | A0A183JJX6 | GMPS ATP-PPase domain-containing protein. | Uncharacterized protein. | 0.544 |
| A0A183K9T6 | SCUD_LOCUS5927 | A0A183K9T6 | A0A183JT87 | GMPS ATP-PPase domain-containing protein. | Uncharacterized protein. | 0.933 |
| A0A183KIH2 | A0A183K9T6 | A0A183KIH2 | A0A183K9T6 | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | GMPS ATP-PPase domain-containing protein. | 0.964 |
| A0A183KIH2 | A0A183KKN6 | A0A183KIH2 | A0A183KKN6 | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | IMPDH domain-containing protein. | 0.977 |
| A0A183KIH2 | A0A183KKQ3 | A0A183KIH2 | A0A183KKQ3 | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Uncharacterized protein. | 0.973 |
| A0A183KIH2 | A0A183KNM0 | A0A183KIH2 | A0A183KNM0 | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | 0.959 |
| A0A183KIH2 | A0A183KTR4 | A0A183KIH2 | A0A183KTR4 | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Pribosyltran domain-containing protein. | 0.977 |
| A0A183KIH2 | A0A183KZG5 | A0A183KIH2 | A0A183KZG5 | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Uncharacterized protein. | 0.964 |
| A0A183KIH2 | SCUD_LOCUS3004 | A0A183KIH2 | A0A183JJX6 | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Uncharacterized protein. | 0.959 |
| A0A183KIH2 | SCUD_LOCUS5927 | A0A183KIH2 | A0A183JT87 | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Uncharacterized protein. | 0.933 |
| A0A183KKN6 | A0A183K9T6 | A0A183KKN6 | A0A183K9T6 | IMPDH domain-containing protein. | GMPS ATP-PPase domain-containing protein. | 0.994 |
| A0A183KKN6 | A0A183KIH2 | A0A183KKN6 | A0A183KIH2 | IMPDH domain-containing protein. | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.977 |