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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A183QVR5Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (138 aa)    
Predicted Functional Partners:
A0A183R3U2
Uncharacterized protein.
    
 
 0.991
A0A183QWJ8
Hat1_N domain-containing protein.
    
 0.982
A0A183R1Y3
Ubiquitin-like domain-containing protein.
   
 0.982
A0A183S644
Uncharacterized protein.
    
 0.982
A0A183QEE2
Uncharacterized protein; Belongs to the actin family.
    
 0.981
A0A183QU22
TPR_REGION domain-containing protein.
    
 0.979
A0A183S005
Uncharacterized protein.
    
 0.979
A0A183R0Z3
RPOLD domain-containing protein.
    
 0.978
A0A183R221
Ubiquitin-like domain-containing protein.
   
 0.978
A0A183QYS2
Uncharacterized protein.
    
 0.977
Your Current Organism:
Schistosoma rodhaini
NCBI taxonomy Id: 6188
Other names: S. rodhaini
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.