STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SIS54728.1Hypothetical protein. (200 aa)    
Predicted Functional Partners:
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
  
 
 0.888
SIS54748.1
Trans-2,3-dihydro-3-hydroxyanthranilate isomerase.
       0.527
SIS54766.1
Uncharacterized conserved protein YjiS, DUF1127 family.
       0.527
SIS54710.1
Ornithine decarboxylase; Belongs to the Orn/Lys/Arg decarboxylase class-II family.
       0.519
SIS44031.1
Hypothetical protein.
   
    0.493
purA
Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
  
 
 0.468
SIS46332.1
GMP synthase-Glutamine amidotransferase.
 
  
 0.467
SIS91160.1
Hypoxanthine phosphoribosyltransferase.
  
 
  0.457
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
    
 0.446
purH
Phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase.
    
  0.444
Your Current Organism:
Neptunomonas antarctica
NCBI taxonomy Id: 619304
Other names: CCTCC AB 209086, KACC 14056, N. antarctica, Neptunomonas antarctica Zhang et al. 2010, Neptunomonas sp. S3-22, strain S3-22
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