node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SIS40529.1 | guaA | SAMN05421760_101126 | SAMN05421760_1011101 | 16S rRNA m(5)C-967 methyltransferase; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.509 |
SIS40529.1 | queE | SAMN05421760_101126 | SAMN05421760_102536 | 16S rRNA m(5)C-967 methyltransferase; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | 7-carboxy-7-deazaguanine synthase, Cx14CxxC type; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.497 |
SIS40529.1 | queF | SAMN05421760_101126 | SAMN05421760_105210 | 16S rRNA m(5)C-967 methyltransferase; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | 7-cyano-7-deazaguanine reductase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). | 0.590 |
SIS40529.1 | rlmH | SAMN05421760_101126 | SAMN05421760_101720 | 16S rRNA m(5)C-967 methyltransferase; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | 23S rRNA (pseudouridine-1915-N(3)-) methyltransferase; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. | 0.652 |
SIS62350.1 | queE | SAMN05421760_102535 | SAMN05421760_102536 | Rhodanese-related sulfurtransferase. | 7-carboxy-7-deazaguanine synthase, Cx14CxxC type; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.468 |
SIT11392.1 | folE | SAMN05421760_11625 | SAMN05421760_101235 | 6-pyruvoyl tetrahydropterin synthase. | GTP cyclohydrolase I. | 0.835 |
SIT11392.1 | guaA | SAMN05421760_11625 | SAMN05421760_1011101 | 6-pyruvoyl tetrahydropterin synthase. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.512 |
SIT11392.1 | queC | SAMN05421760_11625 | SAMN05421760_102302 | 6-pyruvoyl tetrahydropterin synthase. | preQ(0) biosynthesis protein QueC; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.936 |
SIT11392.1 | queE | SAMN05421760_11625 | SAMN05421760_102536 | 6-pyruvoyl tetrahydropterin synthase. | 7-carboxy-7-deazaguanine synthase, Cx14CxxC type; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.963 |
SIT11392.1 | queF | SAMN05421760_11625 | SAMN05421760_105210 | 6-pyruvoyl tetrahydropterin synthase. | 7-cyano-7-deazaguanine reductase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). | 0.910 |
folE | SIT11392.1 | SAMN05421760_101235 | SAMN05421760_11625 | GTP cyclohydrolase I. | 6-pyruvoyl tetrahydropterin synthase. | 0.835 |
folE | queE | SAMN05421760_101235 | SAMN05421760_102536 | GTP cyclohydrolase I. | 7-carboxy-7-deazaguanine synthase, Cx14CxxC type; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.455 |
folE | queF | SAMN05421760_101235 | SAMN05421760_105210 | GTP cyclohydrolase I. | 7-cyano-7-deazaguanine reductase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). | 0.518 |
glmS | guaA | SAMN05421760_10154 | SAMN05421760_1011101 | Glutamine--fructose-6-phosphate transaminase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.665 |
glmS | purF | SAMN05421760_10154 | SAMN05421760_1159 | Glutamine--fructose-6-phosphate transaminase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.862 |
glmS | queC | SAMN05421760_10154 | SAMN05421760_102302 | Glutamine--fructose-6-phosphate transaminase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | preQ(0) biosynthesis protein QueC; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.477 |
glmS | queE | SAMN05421760_10154 | SAMN05421760_102536 | Glutamine--fructose-6-phosphate transaminase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | 7-carboxy-7-deazaguanine synthase, Cx14CxxC type; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.542 |
guaA | SIS40529.1 | SAMN05421760_1011101 | SAMN05421760_101126 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 16S rRNA m(5)C-967 methyltransferase; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | 0.509 |
guaA | SIT11392.1 | SAMN05421760_1011101 | SAMN05421760_11625 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 6-pyruvoyl tetrahydropterin synthase. | 0.512 |
guaA | glmS | SAMN05421760_1011101 | SAMN05421760_10154 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | Glutamine--fructose-6-phosphate transaminase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | 0.665 |