STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SIS76527.12-methylcitrate dehydratase. (494 aa)    
Predicted Functional Partners:
SIS58976.1
2-methylcitrate synthase; Belongs to the citrate synthase family.
 
 0.997
prpB
Methylisocitrate lyase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.
 
  
 0.956
SIS57033.1
Citrate synthase; Belongs to the citrate synthase family.
 
 
 0.946
SIS70695.1
Carboxyvinyl-carboxyphosphonate phosphorylmutase.
 
  
 0.944
SIS96950.1
Aconitase; Belongs to the aconitase/IPM isomerase family.
 
   
 0.938
SIS76479.1
Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate.
  
 
 0.918
SIS58960.1
Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate.
  
 
 0.879
SIS58942.1
2-methylaconitate cis-trans isomerase.
  
 
  0.826
SIS70111.1
4-oxalomesaconate tautomerase.
  
 
  0.826
SIS94394.1
Fatty acid oxidation complex subunit alpha; Involved in the aerobic and anaerobic degradation of long- chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. In the C-terminal section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family.
  
 
  0.766
Your Current Organism:
Neptunomonas antarctica
NCBI taxonomy Id: 619304
Other names: CCTCC AB 209086, KACC 14056, N. antarctica, Neptunomonas antarctica Zhang et al. 2010, Neptunomonas sp. S3-22, strain S3-22
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