STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SIT04383.13-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family. (296 aa)    
Predicted Functional Partners:
SIT04393.1
Enoyl-CoA hydratase/carnithine racemase.
 
 0.995
SIS43201.1
Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.
 
    0.903
SIS40682.1
Pyruvate-ferredoxin/flavodoxin oxidoreductase.
    
  0.890
SIS94394.1
Fatty acid oxidation complex subunit alpha; Involved in the aerobic and anaerobic degradation of long- chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. In the C-terminal section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family.
  
 
 0.841
SIT04373.1
propionyl-CoA synthetase.
  
 
  0.832
SIT04418.1
Methylmalonate-semialdehyde dehydrogenase [acylating].
 
 0.830
SIT10500.1
3-hydroxyisobutyrate dehydrogenase.
  
  
 
0.823
SIS59660.1
Acetyltransferase.
    
  0.804
SIS58976.1
2-methylcitrate synthase; Belongs to the citrate synthase family.
  
 
  0.780
SIS91451.1
Phosphate acetyltransferase.
    
  0.777
Your Current Organism:
Neptunomonas antarctica
NCBI taxonomy Id: 619304
Other names: CCTCC AB 209086, KACC 14056, N. antarctica, Neptunomonas antarctica Zhang et al. 2010, Neptunomonas sp. S3-22, strain S3-22
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