STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SIT07807.1META domain-containing protein. (322 aa)    
Predicted Functional Partners:
SIT07790.1
Predicted transcriptional regulator.
 
 
  0.973
grpE
Molecular chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP [...]
  
  
 0.917
SIS46027.1
VCBS repeat-containing protein.
  
     0.732
SIT02107.1
cation:H+ antiporter.
 
     0.702
SIS74422.1
Hypothetical protein.
  
     0.641
SIS46035.1
Biotin-lipoyl like.
  
    0.633
SIT07855.1
Hypothetical protein.
 
     0.622
SIT01932.1
Peptide/nickel transport system permease protein.
  
     0.599
SIT05684.1
Cholesterol transport system auxiliary component.
  
     0.591
SIS82032.1
Cytidine and deoxycytidylate deaminase zinc-binding region.
  
     0.581
Your Current Organism:
Neptunomonas antarctica
NCBI taxonomy Id: 619304
Other names: CCTCC AB 209086, KACC 14056, N. antarctica, Neptunomonas antarctica Zhang et al. 2010, Neptunomonas sp. S3-22, strain S3-22
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