STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EEX53695.1C-5 cytosine-specific DNA methylase; COG: COG0270; Pfam: PF00145; InterPro: IPR001525; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (403 aa)    
Predicted Functional Partners:
dcm
DNA (cytosine-5-)-methyltransferase; COG: COG0270; Pfam: PF00145; InterPro: IPR001525; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.
  
     0.774
vsr
DNA mismatch endonuclease Vsr; May nick specific sequences that contain T:G mispairs resulting from m5C-deamination.
 
   
 0.757
EEX53713.1
DNA (cytosine-5-)-methyltransferase; COG: COG0863; Pfam: PF01555; InterPro: IPR002941; Belongs to the N(4)/N(6)-methyltransferase family.
 
  
 0.575
EEX53697.1
Hypothetical protein.
       0.493
EEX53696.1
Hypothetical protein.
       0.468
metK
Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
    
 0.441
trmE
tRNA modification GTPase TrmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
  
 
   0.437
EEX51646.1
Helicase C-terminal domain protein; COG: COG4646; Pfam: PF00271.
     
 0.414
Your Current Organism:
Prevotella sp. F0295
NCBI taxonomy Id: 619693
Other names: P. sp. oral taxon 472 str. F0295, Prevotella sp. oral taxon 472 str. F0295
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