| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EEX52487.1 | cobC | HMPREF6745_2001 | HMPREF6745_1997 | OmpA family protein; Pfam: PF00691; InterPro: IPR006665. | Alpha-ribazole phosphatase; Pfam: PF00300; InterPro: IPR013078. | 0.454 |
| EEX52487.1 | cobS | HMPREF6745_2001 | HMPREF6745_1998 | OmpA family protein; Pfam: PF00691; InterPro: IPR006665. | Cobalamin-5-phosphate synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. | 0.479 |
| EEX52487.1 | cobT | HMPREF6745_2001 | HMPREF6745_1999 | OmpA family protein; Pfam: PF00691; InterPro: IPR006665. | Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). | 0.479 |
| EEX52487.1 | cobU | HMPREF6745_2001 | HMPREF6745_2000 | OmpA family protein; Pfam: PF00691; InterPro: IPR006665. | Adenosylcobinamide kinase/adenosylcobinamidephosphate guanylyltransferase; COG: COG2087; Pfam: PF02283; InterPro: IPR003203. | 0.570 |
| EEX52704.1 | cobC | HMPREF6745_1798 | HMPREF6745_1997 | Phosphoglycerate mutase family protein; COG: COG0406; Pfam: PF00300; InterPro: IPR013078; Belongs to the phosphoglycerate mutase family. | Alpha-ribazole phosphatase; Pfam: PF00300; InterPro: IPR013078. | 0.400 |
| EEX52704.1 | cobS | HMPREF6745_1798 | HMPREF6745_1998 | Phosphoglycerate mutase family protein; COG: COG0406; Pfam: PF00300; InterPro: IPR013078; Belongs to the phosphoglycerate mutase family. | Cobalamin-5-phosphate synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. | 0.522 |
| EEX52704.1 | cobT | HMPREF6745_1798 | HMPREF6745_1999 | Phosphoglycerate mutase family protein; COG: COG0406; Pfam: PF00300; InterPro: IPR013078; Belongs to the phosphoglycerate mutase family. | Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). | 0.459 |
| EEX52704.1 | cobU | HMPREF6745_1798 | HMPREF6745_2000 | Phosphoglycerate mutase family protein; COG: COG0406; Pfam: PF00300; InterPro: IPR013078; Belongs to the phosphoglycerate mutase family. | Adenosylcobinamide kinase/adenosylcobinamidephosphate guanylyltransferase; COG: COG2087; Pfam: PF02283; InterPro: IPR003203. | 0.452 |
| EEX54231.1 | cbrD | HMPREF6745_0278 | HMPREF6745_1146 | ATP:cob(I)alamin adenosyltransferase; COG: COG2096; Pfam: PF01923; InterPro: IPR002779; Belongs to the Cob(I)alamin adenosyltransferase family. | ABC transporter, ATP-binding protein; COG: COG1120; Pfam: PF00005; InterPro: IPR003593. | 0.474 |
| EEX54231.1 | cobS | HMPREF6745_0278 | HMPREF6745_1998 | ATP:cob(I)alamin adenosyltransferase; COG: COG2096; Pfam: PF01923; InterPro: IPR002779; Belongs to the Cob(I)alamin adenosyltransferase family. | Cobalamin-5-phosphate synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. | 0.838 |
| EEX54231.1 | cobU | HMPREF6745_0278 | HMPREF6745_2000 | ATP:cob(I)alamin adenosyltransferase; COG: COG2096; Pfam: PF01923; InterPro: IPR002779; Belongs to the Cob(I)alamin adenosyltransferase family. | Adenosylcobinamide kinase/adenosylcobinamidephosphate guanylyltransferase; COG: COG2087; Pfam: PF02283; InterPro: IPR003203. | 0.840 |
| cbrD | EEX54231.1 | HMPREF6745_1146 | HMPREF6745_0278 | ABC transporter, ATP-binding protein; COG: COG1120; Pfam: PF00005; InterPro: IPR003593. | ATP:cob(I)alamin adenosyltransferase; COG: COG2096; Pfam: PF01923; InterPro: IPR002779; Belongs to the Cob(I)alamin adenosyltransferase family. | 0.474 |
| cbrD | cobU | HMPREF6745_1146 | HMPREF6745_2000 | ABC transporter, ATP-binding protein; COG: COG1120; Pfam: PF00005; InterPro: IPR003593. | Adenosylcobinamide kinase/adenosylcobinamidephosphate guanylyltransferase; COG: COG2087; Pfam: PF02283; InterPro: IPR003203. | 0.521 |
| cobC | EEX52487.1 | HMPREF6745_1997 | HMPREF6745_2001 | Alpha-ribazole phosphatase; Pfam: PF00300; InterPro: IPR013078. | OmpA family protein; Pfam: PF00691; InterPro: IPR006665. | 0.454 |
| cobC | EEX52704.1 | HMPREF6745_1997 | HMPREF6745_1798 | Alpha-ribazole phosphatase; Pfam: PF00300; InterPro: IPR013078. | Phosphoglycerate mutase family protein; COG: COG0406; Pfam: PF00300; InterPro: IPR013078; Belongs to the phosphoglycerate mutase family. | 0.400 |
| cobC | cobS | HMPREF6745_1997 | HMPREF6745_1998 | Alpha-ribazole phosphatase; Pfam: PF00300; InterPro: IPR013078. | Cobalamin-5-phosphate synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. | 0.996 |
| cobC | cobT | HMPREF6745_1997 | HMPREF6745_1999 | Alpha-ribazole phosphatase; Pfam: PF00300; InterPro: IPR013078. | Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). | 0.990 |
| cobC | cobU | HMPREF6745_1997 | HMPREF6745_2000 | Alpha-ribazole phosphatase; Pfam: PF00300; InterPro: IPR013078. | Adenosylcobinamide kinase/adenosylcobinamidephosphate guanylyltransferase; COG: COG2087; Pfam: PF02283; InterPro: IPR003203. | 0.933 |
| cobS | EEX52487.1 | HMPREF6745_1998 | HMPREF6745_2001 | Cobalamin-5-phosphate synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. | OmpA family protein; Pfam: PF00691; InterPro: IPR006665. | 0.479 |
| cobS | EEX52704.1 | HMPREF6745_1998 | HMPREF6745_1798 | Cobalamin-5-phosphate synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. | Phosphoglycerate mutase family protein; COG: COG0406; Pfam: PF00300; InterPro: IPR013078; Belongs to the phosphoglycerate mutase family. | 0.522 |