Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EEX52497.1Hypothetical protein; Pfam: PF03993. (587 aa)    
Predicted Functional Partners:
rnpA
Putative ribonuclease P protein component; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
  
 
  0.808
guaA
GMP synthase (glutamine-hydrolyzing) domain protein; Catalyzes the synthesis of GMP from XMP.
     
  0.785
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
     
  0.737
EEX51574.1
Hypothetical protein.
  
     0.671
EEX52404.1
Hypothetical protein.
  
     0.668
EEX52175.1
Hypothetical protein.
  
     0.659
EEX54466.1
Efflux transporter, RND family, MFP subunit; Pfam: PF00529; InterPro: IPR006143; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
  
  
  0.639
EEX52496.1
TrkA C-terminal domain protein; COG: COG2985; Pfam: PF06826,PF02080; InterPro: IPR006512.
       0.619
EEX52176.1
UvrD/REP helicase; Pfam: PF00580; InterPro: IPR000212; Belongs to the helicase family. UvrD subfamily.
  
     0.609
EEX52498.1
CorA-like protein; COG: COG0598; Pfam: PF01544; InterPro: IPR002523.
       0.595
Your Current Organism:
Prevotella sp. F0295
NCBI taxonomy Id: 619693
Other names: P. sp. oral taxon 472 str. F0295, Prevotella sp. oral taxon 472 str. F0295
Server load: low (12%) [HD]