Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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ligADNA ligase (NAD+); DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. (666 aa)    
Predicted Functional Partners:
EEX52501.1
Hypothetical protein; COG: COG3382.
       0.812
EEX52500.1
Putative pantothenate kinase; Pfam: PF03630; InterPro: IPR011602.
       0.806
menA
1,4-dihydroxy-2-naphthoate octaprenyltransferase; Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK); Belongs to the MenA family. Type 1 subfamily.
       0.773
leuS
leucine--tRNA ligase; COG: COG0495; Pfam: PF09334,PF00133,PF08264; InterPro: IPR002302; Belongs to the class-I aminoacyl-tRNA synthetase family.
  
 
 
 0.765
EEX54340.1
UvrD/REP helicase; Pfam: PF00580,PF00929; InterPro: IPR000212.
  
 
 0.761
EEX54053.1
ATP-dependent DNA helicase, RecQ family; COG: COG0514; Pfam: PF00270,PF00271,PF00580; InterPro: IPR004589.
  
  
 0.690
nifJ
Pyruvate synthase; COG: COG0674; Pfam: PF01855,PF01558,PF00037,PF02775; InterPro: IPR011895.
   
   0.683
polA
DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
 
   
 0.679
EEX52503.1
Hypothetical protein.
       0.647
ugd
Nucleotide sugar dehydrogenase; COG: COG1004; Pfam: PF03721,PF00984,PF03720; InterPro: IPR014028.
  
    0.637
Your Current Organism:
Prevotella sp. F0295
NCBI taxonomy Id: 619693
Other names: P. sp. oral taxon 472 str. F0295, Prevotella sp. oral taxon 472 str. F0295
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