Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
nudCHydrolase, NUDIX family; COG: COG2816; Pfam: PF09296,PF09297,PF00293; InterPro: IPR000086; Belongs to the Nudix hydrolase family. (259 aa)    
Predicted Functional Partners:
nadE
NAD+ synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
  
 
 0.914
cobB
Transcriptional regulator, Sir2 family; COG: COG0846; Pfam: PF02146; InterPro: IPR003000; Belongs to the sirtuin family. Class III subfamily.
  
  0.865
cinA
Competence/damage-inducible domain protein CinA; COG: COG1546; Pfam: PF02464; InterPro: IPR008136; Belongs to the CinA family.
    
 0.852
surE
5'/3'-nucleotidase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
   
 
  0.846
EEX53775.1
Ser/Thr phosphatase family protein; COG: COG0737; Pfam: PF00149; InterPro: IPR006179.
    
  0.843
pncB
Nicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family.
    
 0.837
nadD
Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
     
 0.835
ppnK
NAD(+)/NADH kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
     
  0.833
nadC
Nicotinate-nucleotide diphosphorylase (carboxylating); COG: COG0157; Pfam: PF02749,PF01729; InterPro: IPR004393; Belongs to the NadC/ModD family.
     
  0.833
cpdB
5'-nucleotidase, C-terminal domain protein; COG: COG0737; Pfam: PF00149,PF02872; InterPro: IPR006179; Belongs to the 5'-nucleotidase family.
    
  0.758
Your Current Organism:
Prevotella sp. F0295
NCBI taxonomy Id: 619693
Other names: P. sp. oral taxon 472 str. F0295, Prevotella sp. oral taxon 472 str. F0295
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.