STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pepD-2Xaa-His dipeptidase; COG: COG2195; Pfam: PF01546,PF07687; InterPro: IPR001160. (485 aa)    
Predicted Functional Partners:
EEX51914.1
Hypothetical protein.
       0.857
glyA
Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
   
 
 0.816
aspB
Aminotransferase, class I/II; COG: COG0436; Pfam: PF00155; InterPro: IPR004839.
    
  0.803
aspC
Aminotransferase, class I/II; COG: COG0436; Pfam: PF00155; InterPro: IPR004839.
    
  0.803
patB
Aminotransferase, class I/II; COG: COG1168; Pfam: PF00155; InterPro: IPR015421.
    
  0.784
EEX51912.1
Hypothetical protein.
       0.714
EEX51911.1
Outer membrane protein; Pfam: PF03938; InterPro: IPR005632.
       0.633
pepD
Xaa-His dipeptidase; COG: COG2195; Pfam: PF07687; InterPro: IPR001160.
  
  
 
0.624
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
    
 
 0.468
pepP
Peptidase, M24 family; COG: COG0006; Pfam: PF00557; InterPro: IPR000994.
   
 
 0.410
Your Current Organism:
Prevotella sp. F0295
NCBI taxonomy Id: 619693
Other names: P. sp. oral taxon 472 str. F0295, Prevotella sp. oral taxon 472 str. F0295
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.