STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ENSHHUP00000004591Periplakin. (1039 aa)    
Predicted Functional Partners:
ENSHHUP00000013493
Uncharacterized protein; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.
    
 0.671
ENSHHUP00000013610
Uncharacterized protein; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.
    
 0.671
ENSHHUP00000036486
Uncharacterized protein; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.
    
 0.671
ENSHHUP00000003585
Uncharacterized protein.
    
 0.669
ENSHHUP00000036295
Plakophilin 2.
    
 0.669
ENSHHUP00000058932
Plakophilin 1b.
    
 0.669
ENSHHUP00000065667
Plakophilin 1b.
    
 0.669
ENY2
Transcription and mRNA export factor ENY2; Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. The transcription regulatory histone acetylation (HAT) complex SAGA is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex that specifically deubiquitinates histones. The SAGA complex is recruited to specific gene promoters by activators, where it is required for transcription. The TREX-2 complex [...]
    
 0.645
ENY2-2
Transcription and mRNA export factor ENY2; Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. The transcription regulatory histone acetylation (HAT) complex SAGA is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex that specifically deubiquitinates histones. The SAGA complex is recruited to specific gene promoters by activators, where it is required for transcription. The TREX-2 complex [...]
    
 0.645
ENSHHUP00000030454
Transformation/transcription domain-associated protein; Belongs to the PI3/PI4-kinase family.
    
 0.642
Your Current Organism:
Hucho hucho
NCBI taxonomy Id: 62062
Other names: H. hucho, Hucho hucho hucho, huchen
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.