node1 | node2 | node1 annotation | node2 annotation | score |
ENSHHUP00000003676 | ENSHHUP00000010147 | MDM4, p53 regulator; Belongs to the MDM2/MDM4 family. | MDM2 oncogene, E3 ubiquitin protein ligase. | 0.999 |
ENSHHUP00000003676 | ENSHHUP00000013468 | MDM4, p53 regulator; Belongs to the MDM2/MDM4 family. | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | 0.998 |
ENSHHUP00000003676 | ENSHHUP00000019209 | MDM4, p53 regulator; Belongs to the MDM2/MDM4 family. | Ribosomal protein L11; Belongs to the universal ribosomal protein uL5 family. | 0.961 |
ENSHHUP00000003676 | ENSHHUP00000028921 | MDM4, p53 regulator; Belongs to the MDM2/MDM4 family. | Ubiquitin-like domain-containing protein. | 0.987 |
ENSHHUP00000003676 | ENSHHUP00000034518 | MDM4, p53 regulator; Belongs to the MDM2/MDM4 family. | Ribosomal protein L11; Belongs to the universal ribosomal protein uL5 family. | 0.961 |
ENSHHUP00000003676 | ENSHHUP00000045896 | MDM4, p53 regulator; Belongs to the MDM2/MDM4 family. | ANK_REP_REGION domain-containing protein. | 0.989 |
ENSHHUP00000003676 | ENSHHUP00000061550 | MDM4, p53 regulator; Belongs to the MDM2/MDM4 family. | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | 0.998 |
ENSHHUP00000003676 | ENSHHUP00000072941 | MDM4, p53 regulator; Belongs to the MDM2/MDM4 family. | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | 0.998 |
ENSHHUP00000003676 | ENSHHUP00000074872 | MDM4, p53 regulator; Belongs to the MDM2/MDM4 family. | Ribosomal protein S27a. | 0.987 |
ENSHHUP00000003676 | ENSHHUP00000080469 | MDM4, p53 regulator; Belongs to the MDM2/MDM4 family. | Cyclin-dependent kinase inhibitor 2A/B (p15, inhibits CDK4). | 0.989 |
ENSHHUP00000010147 | ENSHHUP00000003676 | MDM2 oncogene, E3 ubiquitin protein ligase. | MDM4, p53 regulator; Belongs to the MDM2/MDM4 family. | 0.999 |
ENSHHUP00000010147 | ENSHHUP00000013468 | MDM2 oncogene, E3 ubiquitin protein ligase. | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | 0.997 |
ENSHHUP00000010147 | ENSHHUP00000019209 | MDM2 oncogene, E3 ubiquitin protein ligase. | Ribosomal protein L11; Belongs to the universal ribosomal protein uL5 family. | 0.995 |
ENSHHUP00000010147 | ENSHHUP00000028921 | MDM2 oncogene, E3 ubiquitin protein ligase. | Ubiquitin-like domain-containing protein. | 0.995 |
ENSHHUP00000010147 | ENSHHUP00000034518 | MDM2 oncogene, E3 ubiquitin protein ligase. | Ribosomal protein L11; Belongs to the universal ribosomal protein uL5 family. | 0.995 |
ENSHHUP00000010147 | ENSHHUP00000045896 | MDM2 oncogene, E3 ubiquitin protein ligase. | ANK_REP_REGION domain-containing protein. | 0.997 |
ENSHHUP00000010147 | ENSHHUP00000061550 | MDM2 oncogene, E3 ubiquitin protein ligase. | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | 0.997 |
ENSHHUP00000010147 | ENSHHUP00000072941 | MDM2 oncogene, E3 ubiquitin protein ligase. | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | 0.997 |
ENSHHUP00000010147 | ENSHHUP00000074872 | MDM2 oncogene, E3 ubiquitin protein ligase. | Ribosomal protein S27a. | 0.995 |
ENSHHUP00000010147 | ENSHHUP00000080469 | MDM2 oncogene, E3 ubiquitin protein ligase. | Cyclin-dependent kinase inhibitor 2A/B (p15, inhibits CDK4). | 0.997 |