STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSHHUP00000013298Transmembrane protein 129, E3 ubiquitin protein ligase. (362 aa)    
Predicted Functional Partners:
ENSHHUP00000008989
Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.
    
 0.954
ENSHHUP00000033402
Uncharacterized protein.
   
  0.856
ENSHHUP00000033408
ATPase_AAA_core domain-containing protein.
   
  0.856
ENSHHUP00000080765
Peroxisomal biogenesis factor 6.
   
  0.856
ENSHHUP00000013524
Uncharacterized protein.
    
 0.847
UBE2J2
Ubiquitin conjugating enzyme E2 J2.
    
 0.847
ENSHHUP00000002886
Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.
    
 0.827
ENSHHUP00000045647
Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.
    
 0.827
ENSHHUP00000053539
Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.
    
 0.827
ENSHHUP00000051046
C1q and TNF related 12.
    
 0.761
Your Current Organism:
Hucho hucho
NCBI taxonomy Id: 62062
Other names: H. hucho, Hucho hucho hucho, huchen
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