STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSHHUP00000060010General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (465 aa)    
Predicted Functional Partners:
ENSHHUP00000016650
General transcription factor IIE, polypeptide 1, alpha.
   
 0.999
ENSHHUP00000017464
General transcription factor IIH subunit.
   
 0.999
ENSHHUP00000019548
General transcription factor IIH, polypeptide 5.
    
 0.999
ENSHHUP00000044318
General transcription factor IIH, polypeptide 3.
   
 0.999
ENSHHUP00000065037
General transcription factor IIH, polypeptide 1.
    
 0.999
ENSHHUP00000087544
Cyclin H; Belongs to the cyclin family.
    
 0.998
ENSHHUP00000000950
ERCC3_RAD25_C domain-containing protein.
  
 0.995
ENSHHUP00000028064
Helicase ATP-binding domain-containing protein.
  
 0.995
ENSHHUP00000064719
DNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively.
    
  0.995
ENSHHUP00000006458
Excision repair cross-complementation group 2.
    
 0.994
Your Current Organism:
Hucho hucho
NCBI taxonomy Id: 62062
Other names: H. hucho, Hucho hucho hucho, huchen
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.