STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EGR_02946Tight junction protein ZO-3. (1164 aa)    
Predicted Functional Partners:
EGR_00065
Uncharacterized protein.
   
 0.898
EGR_00839
Beta catenin.
    
 0.726
EGR_06408
Afadin.
   
 
 0.703
EGR_02758
Afadin.
   
 
 0.703
EGR_03281
Src substrate cortactin.
    
 0.700
EGR_08391
Leucine-rich repeat serine/threonine-protein kinase.
    
 0.683
EGR_08390
Leucine-rich repeat serine/threonine-protein kinase.
    
 0.683
EGR_02537
Protein kinase C; Belongs to the protein kinase superfamily.
    
 0.651
EGR_01453
Vinculin.
   
 
 0.640
EGR_05121
LAM_G_DOMAIN domain-containing protein.
    
 0.631
Your Current Organism:
Echinococcus granulosus
NCBI taxonomy Id: 6210
Other names: E. granulosus, Echinococcus granulosus G1 strain, Echinococcus granulosus G2 strain, Echinococcus granulosus G3 strain, Echinococcus granulosus Tasmanian sheep strain, Echinococcus granulosus buffalo strain, Echinococcus granulosus s. s., Echinococcus granulosus sensu stricto, Echinococcus granulosus sheep strain
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.