STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EGR_09121Inosine triphosphate pyrophosphatase. (186 aa)    
Predicted Functional Partners:
EGR_09920
Adenine phosphoribosyltransferase.
  
 0.984
EGR_03221
Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.
   
 0.976
EGR_04088
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
  
 0.974
EGR_02422
Nucleoside diphosphate kinase 7.
  
 0.971
EGR_05582
Nucleoside diphosphate kinase.
  
 0.970
EGR_08435
GMP synthase [glutamine-hydrolyzing].
  
 
 0.967
EGR_04076
Deoxyuridine 5'-triphosphate nucleotidohydrolase.
  
 0.956
EGR_10122
Guanylate kinase.
  
 
 0.955
EGR_05047
GTP cyclohydrolase I.
  
 
 0.954
EGR_05276
Thymidylate synthase.
  
 
 0.946
Your Current Organism:
Echinococcus granulosus
NCBI taxonomy Id: 6210
Other names: E. granulosus, Echinococcus granulosus G1 strain, Echinococcus granulosus G2 strain, Echinococcus granulosus G3 strain, Echinococcus granulosus Tasmanian sheep strain, Echinococcus granulosus buffalo strain, Echinococcus granulosus s. s., Echinococcus granulosus sensu stricto, Echinococcus granulosus sheep strain
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