STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EGR_07571Endonuclease/exonuclease/phosphatase family domain-containing protein. (506 aa)    
Predicted Functional Partners:
EGR_06102
TFIIS N-terminal domain-containing protein.
   
 0.932
EGR_02879
RNA polymerase-associated protein LEO1.
   
 0.917
EGR_00565
FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...]
   
 0.907
EGR_09023
FACT complex subunit SPT16.
   
 0.881
EGR_00234
Transcription elongation factor SPT5.
   
 0.871
EGR_01848
Transcription elongation factor SPT4; Component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates transcription elongation by RNA polymerase II; Belongs to the SPT4 family.
    
 0.840
EGR_06882
DNA-directed RNA polymerase II subunit RPB4.
    
 0.773
EGR_01963
DNA-directed RNA polymerases I, II, and III subunit RPABC1.
    
 0.761
EGR_01581
DNA-directed RNA polymerase II subunit RPB7.
    
 0.758
EGR_02921
Parafibromin.
   
 0.741
Your Current Organism:
Echinococcus granulosus
NCBI taxonomy Id: 6210
Other names: E. granulosus, Echinococcus granulosus G1 strain, Echinococcus granulosus G2 strain, Echinococcus granulosus G3 strain, Echinococcus granulosus Tasmanian sheep strain, Echinococcus granulosus buffalo strain, Echinococcus granulosus s. s., Echinococcus granulosus sensu stricto, Echinococcus granulosus sheep strain
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.