STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EGR_06214DNA-dependent protein kinase catalytic subunit; Belongs to the PI3/PI4-kinase family. (4075 aa)    
Predicted Functional Partners:
EGR_04231
ATP-dependent DNA helicase 2 subunit 2.
   
 0.985
EGR_01471
ATP-dependent DNA helicase 2 subunit.
    
 0.983
EGR_05295
DNA ligase 4.
   
 0.964
EGR_06080
Target of rapamycin complex subunit lst8.
    
 0.922
EGR_01015
Target of rapamycin complex 2 subunit MAPKAP1.
    
 0.921
EGR_05557
Ras-related GTP-binding protein D.
    
 0.879
EGR_06673
Nibrin.
    
 0.806
EGR_07425
Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.
    
 0.802
EGR_04411
Uncharacterized protein.
   
 0.794
EGR_04412
Rapamycin-insensitive companion of mTOR.
   
 0.794
Your Current Organism:
Echinococcus granulosus
NCBI taxonomy Id: 6210
Other names: E. granulosus, Echinococcus granulosus G1 strain, Echinococcus granulosus G2 strain, Echinococcus granulosus G3 strain, Echinococcus granulosus Tasmanian sheep strain, Echinococcus granulosus buffalo strain, Echinococcus granulosus s. s., Echinococcus granulosus sensu stricto, Echinococcus granulosus sheep strain
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.