STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EGR_03636H(+)/Cl(-) exchange transporter 7; Belongs to the chloride channel (TC 2.A.49) family. (1452 aa)    
Predicted Functional Partners:
EGR_03628
Osteopetrosis associated transmembrane protein.
   
 0.989
EGR_00285
Integrin alpha ina-1; Belongs to the integrin alpha chain family.
      
 0.771
EGR_00417
Nesprin-1.
      
 0.771
EGR_03576
Serine/threonine-protein kinase LATS2.
    
 0.602
EGR_09836
Inositol polyphosphate 5-phosphatase.
   
  
 0.597
MED19
Mediator of RNA polymerase II transcription subunit 19; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
      
 0.585
EGR_00161
U4/U6 small nuclear ribonucleoprotein Prp3.
      
 0.575
EGR_04175
Sodium/hydrogen exchanger 9.
  
  
 0.555
EGR_04173
Glucose-6-phosphate 1-dehydrogenase; Catalyzes the rate-limiting step of the oxidative pentose- phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis.
  
  
 0.554
EGR_02405
Chloride channel nucleotide sensitivea.
      
 0.537
Your Current Organism:
Echinococcus granulosus
NCBI taxonomy Id: 6210
Other names: E. granulosus, Echinococcus granulosus G1 strain, Echinococcus granulosus G2 strain, Echinococcus granulosus G3 strain, Echinococcus granulosus Tasmanian sheep strain, Echinococcus granulosus buffalo strain, Echinococcus granulosus s. s., Echinococcus granulosus sensu stricto, Echinococcus granulosus sheep strain
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