STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EGR_05548Insulin-degrading enzyme; Belongs to the peptidase M16 family. (1022 aa)    
Predicted Functional Partners:
EGR_00261
40S ribosomal protein S27a.
    
 0.885
EGR_11215
Ubiquitin.
    
  0.810
EGR_00625
Ubiquitin.
    
  0.783
EGR_09664
Mitochondrial import receptor subunit TOM70.
   
 
 0.746
EGR_03437
Endothelin-converting enzyme.
      
 0.680
EGR_07173
Lysosomal aspartic protease; Belongs to the peptidase A1 family.
     
 0.662
EGR_09307
Mitochondrial Rho GTPase.
   
 
 0.617
EGR_08134
Mitochondrial import receptor subunit TOM20.
   
 
  0.610
EGR_06107
Ubiquitin.
    
  0.591
EGR_08951
Ubiquitin-conjugating enzyme E2 D2; Belongs to the ubiquitin-conjugating enzyme family.
     
 0.570
Your Current Organism:
Echinococcus granulosus
NCBI taxonomy Id: 6210
Other names: E. granulosus, Echinococcus granulosus G1 strain, Echinococcus granulosus G2 strain, Echinococcus granulosus G3 strain, Echinococcus granulosus Tasmanian sheep strain, Echinococcus granulosus buffalo strain, Echinococcus granulosus s. s., Echinococcus granulosus sensu stricto, Echinococcus granulosus sheep strain
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.