STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yoaCConserved hypothetical protein. (119 aa)    
Predicted Functional Partners:
yafC
Putative transcriptional regulator LYSR-type; Code: K; COG: COG0583; Belongs to the LysR transcriptional regulatory family.
      
 0.733
yceA
Conserved hypothetical protein; Code: R; COG: COG1054; Belongs to the UPF0176 family.
      
 0.733
rpmI
50S ribosomal subunit protein A; Code: J; COG: COG0291; Belongs to the bacterial ribosomal protein bL35 family.
      
 0.733
yieP
Conserved hypothetical protein; Code: K; COG: COG2186.
      
 0.732
yiaJ
Putative regulator; Code: K; COG: COG1414.
      
 0.731
yeiE
Putative LYSR-type transcriptional regulator; Code: K; COG: COG0583; Belongs to the LysR transcriptional regulatory family.
      
 0.730
serC
3-phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
      
 0.719
ilvN
Acetolactate synthase I, valine sensitive, small subunit; Code: E; COG: COG0440.
      
 0.719
dcuC
C4-dicarboxylate anaerobic carrier DcuC; Responsible for the transport of C4-dicarboxylates during anaerobic growth; Belongs to the DcuC/DcuD transporter (TC 2.A.61) family.
      
 0.718
Your Current Organism:
Shigella flexneri
NCBI taxonomy Id: 198214
Other names: S. flexneri 2a str. 301, Shigella flexneri 2a str. 301, Shigella flexneri serotype 2a str. 301
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.