STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yohLConserved hypothetical protein; Code: S; COG: COG1937. (90 aa)    
Predicted Functional Partners:
mexR
Putative transcriptional regulator; Code: K; COG: COG1846.
 
   
 0.760
ybaR
Putative ATPase; Code: P; COG: COG2217.
  
  
 0.727
zntA
Zinc-transporting ATPase; Code: P; COG: COG2217.
  
  
 0.479
fliN
Flagellar motor switch protein FliN; Code: N; COG: COG1886.
    
   0.471
thiM
Hydoxyethylthiazole kinase; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family.
       0.436
thiD
Phosphomethylpyrimidine kinase; Code: H; COG: COG0351.
       0.434
nikA
Periplasmic binding protein for nickel; Code: EP; COG: COG0747.
      
 0.434
macA
Putative membrane protein; Part of the tripartite efflux system MacAB-TolC. MacA stimulates the ATPase activity of MacB by promoting the closed ATP- bound state of MacB, increases the capacity of MacB to bind macrolides such as erythromycin, and provides a physical link between MacB and TolC. Confers resistance against macrolides (By similarity).
 
    0.401
Your Current Organism:
Shigella flexneri
NCBI taxonomy Id: 198214
Other names: S. flexneri 2a str. 301, Shigella flexneri 2a str. 301, Shigella flexneri serotype 2a str. 301
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.