STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
aspAAspartate ammonia-lyase (aspartase); Code: E; COG: COG1027; Belongs to the class-II fumarase/aspartase family. Aspartase subfamily. (493 aa)    
Predicted Functional Partners:
ansB
Periplasmic L-asparaginase II; Code: EJ; COG: COG0252.
 
 
 0.967
ansA
Cytoplasmic L-asparaginase I; Code: EJ; COG: COG0252.
 
 
 0.954
pckA
Phosphoenolpyruvate carboxykinase; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
   
 
 0.912
argH
Argininosuccinate lyase; Code: E; COG: COG0165.
     
0.910
purB
Adenylosuccinate lyase; Code: F; COG: COG0015.
     
 0.905
purA
Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
     
 0.905
ybiK
Putative asparaginase; Code: E; COG: COG1446.
     
 0.903
asnB
Asparagine synthetase B; Similar to Escherichia coli K12 N-acetylglucosamine metabolism gi: 1786890 (251 aa). BLAST with identity of 97% in 251 aa. This CDS contains an in-frame stop codon. The sequence has been checked and is believed to be correct.
     
 0.900
aspC
Aspartate aminotransferase; Code: E; COG: COG1448.
     
  0.900
asnA
Asparagine synthetase A; Code: E; COG: COG2502.
     
  0.900
Your Current Organism:
Shigella flexneri
NCBI taxonomy Id: 198214
Other names: S. flexneri 2a str. 301, Shigella flexneri 2a str. 301, Shigella flexneri serotype 2a str. 301
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