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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A182RM49Uncharacterized protein. (1084 aa)    
Predicted Functional Partners:
A0A182R368
Cleavage and polyadenylation specificity factor subunit 2.
   
 0.953
A0A4Y0BM62
Cleavage and polyadenylation specificity factor subunit 5; Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs. CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals). Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation. The [...]
   
 0.948
A0A4Y0BMU5
Fip1 domain-containing protein.
   
 0.937
A0A4Y0BJ21
Poly(A) polymerase; Polymerase that creates the 3'-poly(A) tail of mRNA's.
   
 0.921
A0A182RM85
Uncharacterized protein.
   
 0.920
A0A182RLI6
CPSF_A domain-containing protein.
   
 0.913
A0A4Y0BDY7
CPSF_A domain-containing protein.
   
 0.913
A0A182RB20
Protein CLP1 homolog; Required for endonucleolytic cleavage during polyadenylation- dependent pre-mRNA 3'-end formation; Belongs to the Clp1 family. Clp1 subfamily.
   
 0.910
A0A182RZP3
Uncharacterized protein.
   
 0.906
A0A182RP69
MHD domain-containing protein; Belongs to the adaptor complexes medium subunit family.
    
 0.898
Your Current Organism:
Anopheles funestus
NCBI taxonomy Id: 62324
Other names: A. funestus
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