node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SKB28812.1 | SKB39985.1 | SAMN05660226_00439 | SAMN05660226_01182 | Hypothetical protein. | HSP20 family protein; Belongs to the small heat shock protein (HSP20) family. | 0.927 |
SKB28812.1 | SKB45168.1 | SAMN05660226_00439 | SAMN05660226_01395 | Hypothetical protein. | ATP-dependent Clp protease ATP-binding subunit ClpC; Belongs to the ClpA/ClpB family. | 0.437 |
SKB28812.1 | SKB94307.1 | SAMN05660226_00439 | SAMN05660226_03917 | Hypothetical protein. | Molecular chaperone HtpG. | 0.897 |
SKB28812.1 | clpB | SAMN05660226_00439 | SAMN05660226_00795 | Hypothetical protein. | ATP-dependent Clp protease ATP-binding subunit ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | 0.437 |
SKB28812.1 | dnaJ | SAMN05660226_00439 | SAMN05660226_01014 | Hypothetical protein. | Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...] | 0.983 |
SKB28812.1 | dnaK | SAMN05660226_00439 | SAMN05660226_01673 | Hypothetical protein. | Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.856 |
SKB39985.1 | SKB28812.1 | SAMN05660226_01182 | SAMN05660226_00439 | HSP20 family protein; Belongs to the small heat shock protein (HSP20) family. | Hypothetical protein. | 0.927 |
SKB39985.1 | SKB45168.1 | SAMN05660226_01182 | SAMN05660226_01395 | HSP20 family protein; Belongs to the small heat shock protein (HSP20) family. | ATP-dependent Clp protease ATP-binding subunit ClpC; Belongs to the ClpA/ClpB family. | 0.879 |
SKB39985.1 | SKB94307.1 | SAMN05660226_01182 | SAMN05660226_03917 | HSP20 family protein; Belongs to the small heat shock protein (HSP20) family. | Molecular chaperone HtpG. | 0.801 |
SKB39985.1 | clpB | SAMN05660226_01182 | SAMN05660226_00795 | HSP20 family protein; Belongs to the small heat shock protein (HSP20) family. | ATP-dependent Clp protease ATP-binding subunit ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | 0.879 |
SKB39985.1 | dnaJ | SAMN05660226_01182 | SAMN05660226_01014 | HSP20 family protein; Belongs to the small heat shock protein (HSP20) family. | Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...] | 0.642 |
SKB39985.1 | dnaK | SAMN05660226_01182 | SAMN05660226_01673 | HSP20 family protein; Belongs to the small heat shock protein (HSP20) family. | Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.794 |
SKB39985.1 | grpE | SAMN05660226_01182 | SAMN05660226_01015 | HSP20 family protein; Belongs to the small heat shock protein (HSP20) family. | Molecular chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP [...] | 0.641 |
SKB39985.1 | lon | SAMN05660226_01182 | SAMN05660226_01001 | HSP20 family protein; Belongs to the small heat shock protein (HSP20) family. | ATP-dependent Lon protease; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner. | 0.482 |
SKB39985.1 | nnrE | SAMN05660226_01182 | SAMN05660226_00594 | HSP20 family protein; Belongs to the small heat shock protein (HSP20) family. | NAD(P)H-hydrate epimerase; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of bot [...] | 0.568 |
SKB39985.1 | rplP | SAMN05660226_01182 | SAMN05660226_00037 | HSP20 family protein; Belongs to the small heat shock protein (HSP20) family. | Large subunit ribosomal protein L16; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family. | 0.512 |
SKB45168.1 | SKB28812.1 | SAMN05660226_01395 | SAMN05660226_00439 | ATP-dependent Clp protease ATP-binding subunit ClpC; Belongs to the ClpA/ClpB family. | Hypothetical protein. | 0.437 |
SKB45168.1 | SKB39985.1 | SAMN05660226_01395 | SAMN05660226_01182 | ATP-dependent Clp protease ATP-binding subunit ClpC; Belongs to the ClpA/ClpB family. | HSP20 family protein; Belongs to the small heat shock protein (HSP20) family. | 0.879 |
SKB45168.1 | SKB94307.1 | SAMN05660226_01395 | SAMN05660226_03917 | ATP-dependent Clp protease ATP-binding subunit ClpC; Belongs to the ClpA/ClpB family. | Molecular chaperone HtpG. | 0.848 |
SKB45168.1 | dnaJ | SAMN05660226_01395 | SAMN05660226_01014 | ATP-dependent Clp protease ATP-binding subunit ClpC; Belongs to the ClpA/ClpB family. | Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...] | 0.900 |