STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SKB40496.1Isocitrate dehydrogenase (NADP). (430 aa)    
Predicted Functional Partners:
SKB63929.1
Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate.
 
 0.985
SKB36754.1
Aconitase.
 
 0.984
SKB88818.1
2-oxoglutarate dehydrogenase E1 component.
   
 
 0.976
leuB
3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
 
0.968
SKB58061.1
Glutamate synthase (NADPH/NADH) large chain.
    
 0.942
SKB30515.1
Catalase; Serves to protect cells from the toxic effects of hydrogen peroxide.
  
 0.939
mdh
Malate dehydrogenase (NAD); Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family.
  
 
 0.935
SKB34023.1
Isocitrate dehydrogenase; Belongs to the monomeric-type IDH family.
    
 0.905
sucC
succinyl-CoA synthetase beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
 
  
 0.880
SKB34298.1
2-methylcitrate synthase; Belongs to the citrate synthase family.
 
 
 0.878
Your Current Organism:
Parapedobacter luteus
NCBI taxonomy Id: 623280
Other names: DSM 22899, JCM 15977, KACC 10955, P. luteus, Parapedobacter luteus Kim et al. 2010, Parapedobacter sp. 4M29, strain 4M29
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