STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SKB45984.1acetyl-CoA C-acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (391 aa)    
Predicted Functional Partners:
SKB39842.1
3-hydroxybutyryl-CoA dehydrogenase.
 0.999
SKB49540.1
3-hydroxyacyl-CoA dehydrogenase.
 
 0.999
SKB93444.1
enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family.
 0.992
SKB65001.1
Enoyl-CoA hydratase/carnithine racemase; Belongs to the enoyl-CoA hydratase/isomerase family.
 
 0.988
SKB40068.1
methylglutaconyl-CoA hydratase.
 
 0.985
SKB88785.1
Hypothetical protein.
  
 0.982
SKB51309.1
acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
  
 
 0.947
SKB37202.1
3-oxoacid CoA-transferase subunit B.
 
 
 0.922
SKB37191.1
3-oxoacid CoA-transferase subunit A.
 
 
 0.919
sucD
succinyl-CoA synthetase alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
  
 0.910
Your Current Organism:
Parapedobacter luteus
NCBI taxonomy Id: 623280
Other names: DSM 22899, JCM 15977, KACC 10955, P. luteus, Parapedobacter luteus Kim et al. 2010, Parapedobacter sp. 4M29, strain 4M29
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.