| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| SKB50245.1 | SKB51309.1 | SAMN05660226_01714 | SAMN05660226_01799 | Succinate dehydrogenase subunit A. | acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | 0.448 |
| SKB50245.1 | SKB54901.1 | SAMN05660226_01714 | SAMN05660226_01889 | Succinate dehydrogenase subunit A. | Amino acid adenylation domain-containing protein. | 0.444 |
| SKB50245.1 | SKB56677.1 | SAMN05660226_01714 | SAMN05660226_02027 | Succinate dehydrogenase subunit A. | Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. | 0.752 |
| SKB50245.1 | SKB73977.1 | SAMN05660226_01714 | SAMN05660226_02907 | Succinate dehydrogenase subunit A. | Malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+). | 0.673 |
| SKB50245.1 | fumC | SAMN05660226_01714 | SAMN05660226_01646 | Succinate dehydrogenase subunit A. | Fumarase, class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. | 0.972 |
| SKB50245.1 | pckA | SAMN05660226_01714 | SAMN05660226_00945 | Succinate dehydrogenase subunit A. | Phosphoenolpyruvate carboxykinase (ATP); Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. | 0.515 |
| SKB51309.1 | SKB50245.1 | SAMN05660226_01799 | SAMN05660226_01714 | acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | Succinate dehydrogenase subunit A. | 0.448 |
| SKB51309.1 | SKB54901.1 | SAMN05660226_01799 | SAMN05660226_01889 | acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | Amino acid adenylation domain-containing protein. | 0.661 |
| SKB51309.1 | SKB54911.1 | SAMN05660226_01799 | SAMN05660226_01890 | acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | Amino acid adenylation domain-containing protein. | 0.808 |
| SKB51309.1 | SKB56677.1 | SAMN05660226_01799 | SAMN05660226_02027 | acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. | 0.803 |
| SKB51309.1 | SKB58061.1 | SAMN05660226_01799 | SAMN05660226_02170 | acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | Glutamate synthase (NADPH/NADH) large chain. | 0.704 |
| SKB51309.1 | SKB73977.1 | SAMN05660226_01799 | SAMN05660226_02907 | acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | Malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+). | 0.903 |
| SKB51309.1 | pckA | SAMN05660226_01799 | SAMN05660226_00945 | acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | Phosphoenolpyruvate carboxykinase (ATP); Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. | 0.900 |
| SKB54901.1 | SKB50245.1 | SAMN05660226_01889 | SAMN05660226_01714 | Amino acid adenylation domain-containing protein. | Succinate dehydrogenase subunit A. | 0.444 |
| SKB54901.1 | SKB51309.1 | SAMN05660226_01889 | SAMN05660226_01799 | Amino acid adenylation domain-containing protein. | acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | 0.661 |
| SKB54901.1 | SKB54911.1 | SAMN05660226_01889 | SAMN05660226_01890 | Amino acid adenylation domain-containing protein. | Amino acid adenylation domain-containing protein. | 0.999 |
| SKB54901.1 | SKB56677.1 | SAMN05660226_01889 | SAMN05660226_02027 | Amino acid adenylation domain-containing protein. | Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. | 0.744 |
| SKB54901.1 | SKB58061.1 | SAMN05660226_01889 | SAMN05660226_02170 | Amino acid adenylation domain-containing protein. | Glutamate synthase (NADPH/NADH) large chain. | 0.953 |
| SKB54901.1 | SKB73977.1 | SAMN05660226_01889 | SAMN05660226_02907 | Amino acid adenylation domain-containing protein. | Malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+). | 0.582 |
| SKB54901.1 | fmt | SAMN05660226_01889 | SAMN05660226_01222 | Amino acid adenylation domain-containing protein. | methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | 0.777 |