STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
smg-8Protein smg-8; Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons. Probable component of kinase complex containing smg-1 and recruited to stalled ribosomes (By similarity). (871 aa)    
Predicted Functional Partners:
smg-9
Protein smg-9; Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons. Probable component of kinase complex containing smg-1 and recruited to stalled ribosomes (By similarity).
    
 0.999
smg-1
Serine/threonine-protein kinase smg-1; Serine/threonine protein kinase involved in mRNA surveillance. Recognizes the substrate consensus sequence [ST]-Q. Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons by phosphorylating smg-2 (By similarity); Belongs to the PI3/PI4-kinase family.
   
 0.995
smg-5
Protein CBR-SMG-5.
     
 0.982
smg-6
Protein CBR-SMG-6.
     
 0.974
CBG25377
Protein CBG25377; Belongs to the PI3/PI4-kinase family.
   
 0.947
let-363
Serine/threonine-protein kinase TOR.
   
 0.788
CBG19371
Protein CBG19371.
      
 0.777
dcap-1
Protein CBR-DCAP-1.
   
 
 0.773
smgl-2
Protein CBR-SMGL-2.
   
  
 0.756
smgl-1
Protein CBR-SMGL-1.
      
 0.743
Your Current Organism:
Caenorhabditis briggsae
NCBI taxonomy Id: 6238
Other names: C. briggsae, Caenorhabditis briggsae AF16
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.