STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ser-7Protein CBR-SER-7; Belongs to the G-protein coupled receptor 1 family. (427 aa)    
Predicted Functional Partners:
gar-3
Protein CBR-GAR-3; Belongs to the G-protein coupled receptor 1 family.
   
 
 
0.929
gpa-12
Guanine nucleotide-binding protein alpha-12 subunit; Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. May play a role in resistance to fungal infection in the epidermis by regulating the up-regulation of several antimicrobial peptides of the NLP and CNC families. Upstream of plc-3, egl-8, tpa-1 and the p38-like pathway, required for the expression of antimicrobial peptide nlp-29 in the epidermis in response to fungal infection or physical injury; Belongs to the G-alpha family.
    
 0.929
ser-1
Protein CBR-SER-1; Belongs to the G-protein coupled receptor 1 family.
    
0.921
ser-4
Protein CBR-SER-4; Belongs to the G-protein coupled receptor 1 family.
  
  
0.917
mod-1
Protein CBR-MOD-1; Belongs to the ligand-gated ion channel (TC 1.A.9) family.
      
 0.856
mod-5
Protein CBR-MOD-5.
   
 
 0.785
tph-1
Protein CBR-TPH-1.
   
  
 0.778
flp-21
Protein CBR-FLP-21.
    
 
 0.666
gsa-1
Protein CBR-GSA-1.
    
 0.647
bas-1
Protein CBR-BAS-1.
      
 0.640
Your Current Organism:
Caenorhabditis briggsae
NCBI taxonomy Id: 6238
Other names: C. briggsae, Caenorhabditis briggsae AF16
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.