STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ifc-2Intermediate filament protein ifc-2; Cytoplasmic intermediate filaments provide mechanical strength to cells. (621 aa)    
Predicted Functional Partners:
ifo-1
Protein CBR-TTM-4.
   
 
 0.882
CBG08139
Protein CBG08139.
      
 0.741
ifa-1
Protein CBR-IFA-1; Belongs to the intermediate filament family.
  
0.707
erm-1
Protein CBR-ERM-1.
   
  
 0.652
CBG03383
Protein CBG03383.
      
 0.642
CBG14380
Protein CBG14380.
      
 0.632
ifb-2
Protein CBR-IFB-2, isoform a; Belongs to the intermediate filament family.
  
0.585
CBG05781
Golgi apparatus membrane protein TVP23 homolog.
      
 0.564
baf-1
Barrier-to-autointegration factor 1; DNA-binding protein which plays an essential role in nuclear envelope formation. Required for normal chromosome segregation during mitosis. Associates with the nuclear lamina via its interaction with LEM domain containing proteins emr-1 and lem-2 (By similarity). Belongs to the BAF family.
   
 0.560
CBG23791
Major sperm protein; Central component in molecular interactions underlying sperm crawling. Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod.
     
 0.532
Your Current Organism:
Caenorhabditis briggsae
NCBI taxonomy Id: 6238
Other names: C. briggsae, Caenorhabditis briggsae AF16
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.