STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CBG09584Polyprenol reductase; Plays a key role in early steps of protein N-linked glycosylation by being required for the conversion of polyprenol into dolichol. Dolichols are required for the synthesis of dolichol-linked monosaccharides and the oligosaccharide precursor used for N- glycosylation. Acts as a polyprenol reductase that promotes the reduction of the alpha-isoprene unit of polyprenols into dolichols in a NADP-dependent mechanism (By similarity). (309 aa)    
Predicted Functional Partners:
dolk-1
Protein CBG13324.
     
 0.965
CBG20661
Diphosphomevalonate decarboxylase; Performs the first committed step in the biosynthesis of isoprenes.
      
 0.643
fdps-1
Protein CBR-FDPS-1; Belongs to the FPP/GGPP synthase family.
   
  
 0.642
glc-3
Protein CBR-GLC-3; Belongs to the ligand-gated ion channel (TC 1.A.9) family.
      
 0.632
idi-1
Protein CBR-IDI-1.
      
 0.626
CBG03250
Protein CBG03250.
      
 0.583
art-1
Protein CBR-ART-1.
    
 
0.578
algn-6
Alpha-1,3-glucosyltransferase; Belongs to the ALG6/ALG8 glucosyltransferase family.
      
 0.571
algn-8
Alpha-1,3-glucosyltransferase; Belongs to the ALG6/ALG8 glucosyltransferase family.
      
 0.503
algn-11
Protein CBG15348.
   
  
 0.497
Your Current Organism:
Caenorhabditis briggsae
NCBI taxonomy Id: 6238
Other names: C. briggsae, Caenorhabditis briggsae AF16
Server load: low (24%) [HD]