STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cls-2Protein CLASP-2; Probable microtubule plus-end tracking protein that promotes the stabilization of dynamic microtubules. Required for the formation of mitotic and meiotic spindles. Specifically promotes the polymerization of kinetochore-bound microtubules. Also required for cytoplasmic streaming (By similarity). (791 aa)    
Predicted Functional Partners:
klp-19
Protein CBR-KLP-19; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
      
 0.816
dyci-1
Protein CBR-DYCI-1.
    
 
 0.726
bub-1
Protein CBR-BUB-1.
     
 0.713
CBG12075
Protein CBG12075.
     
 0.713
CBG21913
Protein CBG21913.
     
 0.713
zyg-9
Protein CBR-ZYG-9.
   
 
 0.703
nud-2
Protein CBR-NUD-2.
      
 0.702
klp-7
Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
   
 
 0.702
bub-3
Protein CBR-BUB-3.
    
 0.700
air-2
Aurora/IPL1-related protein kinase 2; Serine/threonine-protein kinase which mediates both meiotic and mitotic chromosome segregation. Required for histone H3 'Ser-10' phosphorylation. Phosphorylates tlk-1 and zen-4 (By similarity).
     
 0.691
Your Current Organism:
Caenorhabditis briggsae
NCBI taxonomy Id: 6238
Other names: C. briggsae, Caenorhabditis briggsae AF16
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.