STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mett-10U6 small nuclear RNA (adenine-(43)-N(6))-methyltransferase; RNA N6-methyltransferase that mediates N6-methylation of adenine of U6 small nuclear RNA (U6 snRNA). Involved in mRNA splicing. Required for gamete production, inhibiting germ cell proliferative fate and ensuring germ cell meiotic development. Also promotes progression of the mitotic cell cycle in those germ cells that continue to proliferate. Plays a role in the development of the vulva, somatic gonad and embryo; Belongs to the methyltransferase superfamily. METTL16/RlmF family. (481 aa)    
Predicted Functional Partners:
dlc-1
Dynein light chain.
    
 
 0.669
CBG02979
Protein CBG02979.
   
  
 0.584
metl-5
Protein CBG17981.
      
 0.564
damt-1
Protein CBG02487; Belongs to the MT-A70-like family.
      
 0.544
prp-4
Protein CBR-PRP-4.
   
  
 0.540
CBG21009
Protein CBG21009.
    
 
 0.525
grld-1
Protein CBR-GRLD-1.
      
 0.523
thoc-2
Protein CBR-THOC-2.
      
 0.514
CBG00961
rRNA adenine N(6)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.
   
  
 0.503
pfas-1
Protein CBG18026.
      
 0.502
Your Current Organism:
Caenorhabditis briggsae
NCBI taxonomy Id: 6238
Other names: C. briggsae, Caenorhabditis briggsae AF16
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