STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
spd-2Spindle-defective protein 2; Required both for centrosome duplication and maturation. Required for pericentriolar material (PCM) recruitment. (829 aa)    
Predicted Functional Partners:
npp-11
Protein CBR-NPP-11.
   
 0.999
npp-22
Nucleoporin ndc-1; Component of the nuclear pore complex (NPC), which plays a key role in de novo assembly and insertion of NPC in the nuclear envelope; Belongs to the NDC1 family.
   
 0.978
spd-5
Protein CBR-SPD-5.
   
 
 0.971
npp-5
Nuclear pore complex protein; Functions as a component of the nuclear pore complex (NPC).
   
 0.967
npp-2
Nuclear pore complex protein Nup85; Functions as a component of the nuclear pore complex (NPC).
   
 0.966
npp-15
Protein CBR-NPP-15.
   
 0.966
npp-13
Nuclear pore protein.
   
 0.965
npp-3
Protein CBR-NPP-3.
   
 0.964
npp-20
Protein SEC13 homolog; Functions as a component of the nuclear pore complex (NPC) and the COPII coat; Belongs to the WD repeat SEC13 family.
    
 0.963
CBG05170
Protein CBG05170.
    
 0.962
Your Current Organism:
Caenorhabditis briggsae
NCBI taxonomy Id: 6238
Other names: C. briggsae, Caenorhabditis briggsae AF16
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.