STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lin-28Protein lin-28; Heterochronic protein which controls the choice of stage specific cell fates. Regulates the timing of the second larval stage events (L2 events) in the hypodermis (By similarity); Belongs to the lin-28 family. (237 aa)    
Predicted Functional Partners:
lin-14
Protein lin-14; Heterochronic protein which controls the choice of stage specific cell fates. Involved in the temporal progression of vulval fate patterning, possibly by inhibiting lin-12. Acts as a transcription factor involved in the stage-specific repression of insulin/insulin- like growth factor gene ins-33.
      
 0.954
sox-2
Protein CBR-SOX-2.
   
 0.942
lin-41
Protein CBR-LIN-41.
    
 
 0.897
hbl-1
Protein CBR-HBL-1.
    
 
 0.870
hrp-1
Protein CBR-HRP-1.
   
 0.831
lin-46
Molybdopterin molybdenumtransferase; Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released.
      
 0.813
pup-2
Protein CBR-PUP-2.
   
 0.810
daf-12
Protein CBR-DAF-12.
    
 
 0.790
lin-29
Protein CBR-LIN-29.
    
 
 0.788
CBG01634
Protein CBG01634.
      
 0.777
Your Current Organism:
Caenorhabditis briggsae
NCBI taxonomy Id: 6238
Other names: C. briggsae, Caenorhabditis briggsae AF16
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