STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sta-1Signal transducer and activator of transcription 1; Carries out a dual function: signal transduction and activation of transcription. Activated STAT proteins play a role in repression of dauer formation. Neuronal expression is held in check by negative signals through the TGF-beta pathway that target the daf-3 transcription factor (By similarity). (713 aa)    
Predicted Functional Partners:
let-23
Receptor protein-tyrosine kinase.
    
 0.976
gei-17
Protein CBR-GEI-17.
   
 0.928
CBG01136
Protein CBG01136.
   
 0.864
miz-1
Protein CBG17627.
   
 0.828
ikke-1
Protein CBR-IKKE-1.
   
 0.827
src-2
Tyrosine-protein kinase.
   
 0.781
CBG14937
Tyrosine-protein kinase.
   
 0.781
src-1
Tyrosine-protein kinase.
   
 0.781
actl-1
Protein CBG05082.
   
 0.780
CBG19761
Protein CBG19761.
   
 0.778
Your Current Organism:
Caenorhabditis briggsae
NCBI taxonomy Id: 6238
Other names: C. briggsae, Caenorhabditis briggsae AF16
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