STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CBG18997Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid; Belongs to the alkaline ceramidase family. (272 aa)    
Predicted Functional Partners:
asah-1
Protein CBR-ASAH-1; Belongs to the acid ceramidase family.
     
 0.975
CBG15382
Protein CBG15382; Belongs to the acid ceramidase family.
     
 0.975
asah-2
Protein CBG00863; Belongs to the acid ceramidase family.
     
 0.975
cerk-1
Protein CBG12724.
    
 0.972
ttm-5
Protein CBR-TTM-5; Belongs to the fatty acid desaturase type 1 family. DEGS subfamily.
   
 
 0.968
sms-1
Protein CBR-SMS-1.
     
 0.967
sphk-1
Protein CBR-SPHK-1.
    
 0.947
lagr-1
Protein CBR-LAGR-1.
    
 0.941
hyl-2
Protein CBR-HYL-2.
    
 0.941
hyl-1
Protein CBR-HYL-1.
    
 0.941
Your Current Organism:
Caenorhabditis briggsae
NCBI taxonomy Id: 6238
Other names: C. briggsae, Caenorhabditis briggsae AF16
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.