Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
mtx-1Metaxin-1 homolog; Involved in transport of proteins into the mitochondrion. Essential for embryonic development (By similarity). (312 aa)    
Predicted Functional Partners:
mtx-2
Protein CBR-MTX-2.
  
0.995
tomm-40
Mitochondrial import receptor subunit TOM40 homolog; Channel-forming protein essential for import of protein precursors into mitochondria. Specifically required for nnt-1 accumulation in the mitochondria and may be involved in the secretion of daf-28/insulin from the mitochondria. Required for embryonic and larval development.
   
 0.987
gop-3
Protein CBR-GOP-3.
   
 0.986
tomm-22
Protein CBR-TOMM-22.
    
 0.984
tomm-7
Protein CBR-TOMM-7.
    
 0.958
tomm-20
Mitochondrial import receptor subunit TOM20 homolog; Central component of the receptor complex responsible for the recognition and translocation of cytosolically synthesized mitochondrial preproteins. Together with TOM22 functions as the transit peptide receptor at the surface of the mitochondrion outer membrane and facilitates the movement of preproteins into the translocation pore (By similarity).
    
 0.956
CBG23654
Protein CBG23654.
   
 0.948
lgg-1
Protein lgg.
   
 0.925
lgg-2
Protein lgg.
   
 0.917
tomm-70
Protein CBG06925.
    
 0.897
Your Current Organism:
Caenorhabditis briggsae
NCBI taxonomy Id: 6238
Other names: C. briggsae, Caenorhabditis briggsae AF16
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