STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
myo-3Myosin-3; Essential for muscle contraction. Involved in ovulation likely by regulating the contraction of gonadal myoepithelial sheath cells. (1969 aa)    
Predicted Functional Partners:
mlc-4
Protein CBR-MLC-4.
   
 0.917
mlc-3
Protein CBR-MLC-3.
   
 0.913
mlc-5
Protein CBR-MLC-5.
   
 0.909
unc-54
Protein CBR-UNC-54; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
  
0.900
Cbr-mlc-1
Protein CBR-MLC-2.2.
   
 0.878
rol-6
Protein CBR-ROL-6.
    
 
 0.857
mlc-7
Protein CBG18268.
   
 0.852
atn-1
Protein CBR-ATN-1.
   
 0.839
deb-1
Protein CBR-DEB-1, isoform a.
   
 0.831
lev-11
Tropomyosin; Tropomyosin, in association with the troponin complex, plays a central role in the calcium dependent regulation of muscle contraction. Involved in muscle actin filament organization and muscle arm extension and morphology. Also has a role in male mating behavior by regulating the copulatory spicules. Binds to F-actin (By similarity).
   
 0.830
Your Current Organism:
Caenorhabditis briggsae
NCBI taxonomy Id: 6238
Other names: C. briggsae, Caenorhabditis briggsae AF16
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