STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
unc-62Homeobox protein unc-62; Acts redundantly with ceh-20 and ceh-40 to perform overlapping roles during embryogenesis. Required for postembryonic development of the ectoderm, including the Q, V and P cell lineages, playing a crucial role in ensuring that these cells and their descendants undergo their invariant patterns of cell division, migration, fusion and morphogenesis. Has a role in the mig-13 pathway to promote anterior migration of neuroblasts in the Q lineage. Required for multiple roles in regulating vulva development (By similarity). Belongs to the TALE/MEIS homeobox family. (725 aa)    
Predicted Functional Partners:
ceh-20
Protein CBR-CEH-20.
   
0.931
ceh-40
Protein CBG05292.
  
0.919
ceh-60
Protein CBR-CEH-60.
  
0.919
lin-39
Protein CBR-LIN-39.
   
 0.797
mab-5
Protein CBR-MAB-5.
   
 0.725
php-3
Protein CBR-PHP-3.
    
 
 0.716
nob-1
Protein CBG23031.
    
 
 0.711
yap-1
Protein CBG04520.
    
 0.669
CBG16493
Protein CBG16493; Belongs to the protein kinase superfamily.
   
 
 0.648
CBG00043
Protein CBG00043.
   
 0.640
Your Current Organism:
Caenorhabditis briggsae
NCBI taxonomy Id: 6238
Other names: C. briggsae, Caenorhabditis briggsae AF16
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